Table of Contents
- 1 What does picric acid contain?
- 2 Does picric acid contain group?
- 3 Is picric acid harmful?
- 4 Why is phenol acidic than alcohol?
- 5 How do you prepare for Trinitrophenol?
- 6 Can I use Vitamin C with salicylic acid?
- 7 Why does picric acid cause proteins to precipitate?
- 8 How is picric acid used to stain DNA?
What does picric acid contain?
Picric acid is a C-nitro compound comprising phenol having three nitro substtituents at the 2-, 4- and 6-positions. It has a role as an explosive, an antiseptic drug and a fixative. It derives from a 1,3,5-trinitrobenzene and a phenol. It is a conjugate acid of a picrate anion.
Does picric acid contain group?
From above structure it is clear that Picric Acid no$ – COOH$group.
Which is also known as picric acid?
picric acid, also called 2,4,6-trinitrophenol, pale yellow, odourless crystalline solid that has been used as a military explosive, as a yellow dye, and as an antiseptic. The French began using it in 1886 as a bursting charge for shells under the name of melinite.
How picric acid is formed?
Picric acid: Picric acid is basically prepared from phenol by reacting phenol with concentrated sulphuric acid and concentrated nitric acid. The nitro groups from nitric acid attacks on ortho and para positions which is the best suitable and stable position for the newly formed compound which is picric acid.
Is picric acid harmful?
Picric acid is toxic by skin contact, ingestion or inhalation causing skin discolouration, skin sensitisation and in high concentrations kidney and liver damage. However in addition to its toxicity, picric acid can present a risk of explosion when encountered as a dry solid (in particular when crystalline).
Why is phenol acidic than alcohol?
Phenols are much more acidic than alcohols because the negative charge in the phenoxide ion is not localized on the oxygen atom, as it is in an alkoxide ion, but is delocalized-it is shared by a number of carbon atoms in the benzene ring.
What is name of h2so4?
Sulfuric acid
Sulfuric acid/IUPAC ID
sulfuric acid, sulfuric also spelled sulphuric (H2SO4), also called oil of vitriol, or hydrogen sulfate, dense, colourless, oily, corrosive liquid; one of the most commercially important of all chemicals.
How do you make TNT in a lab?
First, toluene is nitrated with a mixture of sulfuric and nitric acid to produce mononitrotoluene (MNT). The MNT is separated and then renitrated to dinitrotoluene (DNT). In the final step, the DNT is nitrated to trinitrotoluene (TNT) using an anhydrous mixture of nitric acid and oleum.
How do you prepare for Trinitrophenol?
(i) Phenol on reaction with concentrated HNO3 results in the formation of 2,4,6-Trinitrophenol or Picric acid. ii) 2-methyl propene can be obtained from 2-methyl propanol by the reaction of the later with alc. KOH.
Can I use Vitamin C with salicylic acid?
Can I use vitamin C with AHAs/BHAs? Vitamin C is effectively an acid (it’s sometimes known as ascorbic acid), so layering it with AHAs and BHAs like glycolic, salicylic, and lactic acids is a big no-no.
Which is the best description of picric acid?
IDENTIFICATION: Picric acid is a colorless to pale yellow solid. It is odorless and intensely bitter. It is soluble in water. USE: Picric acid is used in the manufacture of explosives, matches and electric batteries. It is used in the leather and textile industries.
Is it OK to use picric acid alone?
Except when sometimes used to secondary fix sections before trichrome staining, picric acid is never used alone. It is commonly mixed with ethanol, formalin and acetic acid and is considered compatible with most other fixing agents. Aftertreatment Conflicting advice is given for the aftertreatment of picric acid fixed tissues.
Why does picric acid cause proteins to precipitate?
It is believed that it forms picrates with basic amino acids and in the process causes the proteins to precipitate.
How is picric acid used to stain DNA?
Bouin solution is a popular fixative solution for histology specimens that contains picric acid. It enhances the staining of acid dyes, but it can also cause any DNA in the sample to be hydrolyzed. Picric acid reacts with hydrogen cyanide to produce red isopurpurate (HCN).