How much sibutramine should I take?

How much sibutramine should I take?

The recommended starting dose of MERIDIA (sibutramine hydrochloride monohydrate) is 10 mg administered once daily with or without food. If there is inadequate weight loss, the dose may be titrated after four weeks to a total of 15 mg once daily.

How long does sibutramine take to work?

Sibutramine is metabolized by cytochrome P450 isozyme CYP3A4 into two pharmacologically-active primary and secondary amines (called active metabolites 1 and 2) with half-lives of 14 and 16 hours, respectively. Peak plasma concentrations of active metabolites 1 and 2 are reached after three to four hours.

What is etodolac 500 mg used for?

Etodolac tablets, capsules, and extended-release (long-acting) tablets are used to relieve pain, tenderness, swelling, and stiffness caused by osteoarthritis (arthritis caused by a breakdown of the lining of the joints) and rheumatoid arthritis (arthritis caused by swelling of the lining of the joints).

What does sibutramine do to the body?

Sibutramine is an anti-obesity drug that produces short-term and modest body weight reductions mainly due to its appetite-suppressing effect. Despite being a useful drug in obesity treatment, awareness about the loss of effectiveness and detrimental side effects of sibutramine has recently emerged.

How often can I take etodolac?

Adults—200 to 400 milligrams (mg) every 6 to 8 hours. However, the dose usually is not more than 1000 mg per day. Children—Use and dose must be determined by your doctor.

Does etodolac work right away?

It is available as a generic drug and can only be obtained with a doctor’s prescription. Etodolac has a half-life of around six to seven hours and reaches peak concentrations in the blood one to two hours after ingesting it. It is usually taken two to three times daily for pain from arthritis.

Does sibutramine give you energy?

The antiobesity activity of sibutramine results from its dual mode of action: it reduces energy intake by increasing satiety (6), and it increases energy expenditure by stimulating thermogenesis (7, 8).

How many mg of sibutramine can you take in one day?

Doses above 15 mg daily are not recommended. Alternatively, for patients who do not tolerate the 10 mg dose well, either discontinuation of the drug or a dose of 5 mg orally once a day may be appropriate (depending on the severity of the adverse reaction to the 10 mg dose).

How long does it take to lose weight with sibutramine?

Your doctor may occasionally change your dose to make sure you get the best results. Sibutramine can be taken with or without food. You should lose at least 4 pounds during the first 4 weeks of taking sibutramine and eating a low calorie diet. Tell your doctor if you do not lose at least 4 pounds after taking the medication for 4 weeks.

When to call the doctor about sibutramine side effects?

Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. Stop using sibutramine and call your doctor at once if you have a serious side effect such as:

What to do if you overdose on sibutramine?

Does Sibutramine Capsule interact with other drugs you are taking? If someone has overdosed and has serious symptoms such as passing out or trouble breathing , call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222.