Table of Contents
- 1 Who invented hydrochlorothiazide?
- 2 What drug company makes losartan?
- 3 What is the name brand for hydrochlorothiazide?
- 4 Does losartan come from China?
- 5 Is losartan safe now 2021?
- 6 When did hydrochlorothiazide become available as a generic?
- 7 How is hydrochlorothiazide made in aqueous alkaline solution?
Who invented hydrochlorothiazide?
deStevens helped develop drug treatments for illnesses like tuberculosis, epilepsy and arthritis. But it was for his work on diuretics that he is best known. In 1955, Dr. deStevens joined Ciba Pharmaceutical in Summit as a senior research chemist, and discovered two diuretics, hydrochlorothiazide and cyclopenthiazide.
Who produced losartan?
Sandoz Inc. Losartan Potassium Hydrochlorothiazide product is manufactured by Lek Pharmaceuticals dd, Ljubljana, Slovenia.
What drug company makes losartan?
Merck & Co’s new angiotensin II inhibitor Cozaar (losartan potassium) has been approved by the US Food and Drug Administration for the management of patients with hypertension. Merck will position the drug as having the efficacy of ACE inhibitors and a cleaner side-effect profile.
When was hydrochlorothiazide introduced?
Hydrochlorothiazide was granted FDA approval on 12 February 1959.
What is the name brand for hydrochlorothiazide?
Hydrochlorothiazide (HCTZ) is a thiazide diuretic (aka a “water pill”) used to treat high blood pressure or swelling (edema) by helping your body get rid of excess water and salt. It’s sold as a generic drug and under the brand names Microzide, HydroDiuril, and Oretic.
Is losartan made in China?
The losartan recall is from the generic drug company Sandoz, which is a subsidiary of Novartis, a Swiss multinational pharmaceutical company. The active pharmaceutical ingredient (the real medicine) was made in China by Zhejiang Huahai Pharmaceutical Co.
Does losartan come from China?
Drug company Sandoz says it has recalled one lot of losartan potassium hydrochlorothiazide tablets. The impurity, known as NDEA, was found in the drug’s key ingredient made by Zhejiang Huahai Pharmaceutical Co. in China.
What brands are thiazide diuretics?
Thiazide diuretics
| Generic Name | Brand Name |
|---|---|
| chlorthalidone and chlorthalidone combinations | Clorpres, Tenoretic, Thalitone |
| hydrochlorothiazide and hydrochlorothiazide combinations | Capozide, Dyazide, Hyzaar, Lopressor HCT, Maxzide, Prinzide |
Is losartan safe now 2021?
On April 26, 2021, the FDA designated the recalls Class II, communicating use of the drug may cause temporary or medically reversible adverse health consequences or a remote possibility of serious harm. Losartan is a prescription drug used to treat high blood pressure.
What are the names of medications that contain hydrochlorothiazide?
Medications containing hydrochlorothiazide: hydrochlorothiazide systemic. Brand names: HydroDIURIL, Microzide, Esidrix, Oretic. Drug class(es): thiazide diuretics. Hydrochlorothiazide systemic is used in the treatment of: Diabetes Insipidus. Edema. High Blood Pressure.
When did hydrochlorothiazide become available as a generic?
Two companies, Merck and Ciba, state they discovered the medication which became commercially available in 1959. It is on the World Health Organization’s List of Essential Medicines. It is available as a generic drug and is relatively affordable.
What is the physiologic effect of hydrochlorothiazide?
Hydrochlorothiazide is a Thiazide Diuretic. The physiologic effect of hydrochlorothiazide is by means of Increased Diuresis. The chemical classification of hydrochlorothiazide is Thiazides. Hydrochlorothiazide is a short acting thiazide diuretic. Hydrochlorothiazide (HCTZ) is widely used to treat hypertension and edema.
How is hydrochlorothiazide made in aqueous alkaline solution?
Hydrochlorothiazide is synthesized by either the reaction of para-formaldehyde with 5-chloro-2,4-disulfamoylaniline in nonaqueous media, or the reaction of formaldehyde with 6-chloro-7-sulfamoyl-2H-1,2,4-benzothiadiazine-1,1-dioxide in aqueous alkaline solution.