Table of Contents
- 1 How do you take care of a zebrafish?
- 2 What is the regulation that provides guidelines for laboratory experimentation on microorganisms plants and animals?
- 3 What do you need for zebra fish?
- 4 Why are zebrafish good model organisms?
- 5 What are Cpcsea guidelines?
- 6 What are the advantages of using zebrafish for research?
- 7 Are there any laws to regulate animal research?
- 8 What is the federal policy on laboratory animals?
How do you take care of a zebrafish?
To maintain zebrafish in a healthy condition, it is important to provide them with a clean environment in a properly functioning aquarium system. An important part of this is changing system filters regularly so that all the tanks receive proper water flow and clean water.
What is the regulation that provides guidelines for laboratory experimentation on microorganisms plants and animals?
The biosafety regulation for laboratories involving microbiologic pathogens (State Council 2004; State Administration of Environmental Protection 2006; National Standards Committee 2008) should be followed, as appropriate.
Who prepares the Guide for the Care and Use of Laboratory Animals?
*For guidance throughout these Principles, the reader is referred to the Guide for the Care and Use of Laboratory Animals prepared by the Institute of Laboratory Animal Resources, National Academy of Sciences. **Published in the Federal Register, May 20, 1985, Vol. 50, No.
What are the disadvantages of using zebrafish for research?
Disadvantages: They require water systems to maintain them. They are not mammals and are not as closely related to humans as a mouse is. Reverse genetics has not been worked out for zebrafish as it has in the mouse.
What do you need for zebra fish?
Because zebrafish are native to tropical conditions, they require relatively warm water but can adjust to variable temperatures between 70°F -90 °F (5, 6) with an accepted optimum temperature of 83°F (6).
Why are zebrafish good model organisms?
Zebrafish embryos are nearly transparent which allows researchers to easily examine the development of internal structures. As zebrafish eggs are fertilised and develop outside the mother’s body it is an ideal model organism for studying early development. Zebrafish have a similar genetic structure to humans.
What are the major laws and guidelines that govern animal research?
The Animal Welfare Act, signed into law in 1966 and updated by several amendments, is the only federal law that regulates the treatment of animals in research, exhibition, and transport, and by dealers. It applies to all research involving animals in the U.S., but it does not apply to all animals.
What are the laws that affect the use of animals in research teaching and testing?
The Animal Welfare Act (AWA) is the federal law governing the care and use of laboratory animals in the United States. Facilities covered by the AWA that use animals for research, testing, or education must form an Institutional Animal Care and Use Committee (IACUC) to oversee their animal programs.
What are Cpcsea guidelines?
The Central Government has constituted a Committee for the Purpose of Control and Supervision of Experiments on Animals (CPCSEA) which is duty bound to take all such measures as may be necessary to ensure that animals are not subjected to unnecessary pain or suffering before, during or after the performance of …
What are the advantages of using zebrafish for research?
Benefits of the zebrafish The zebrafish is small and robust. They are cheaper to maintain than mice. Break of daylight triggers mating in zebrafish (many other fish only lay eggs in the dark). Zebrafish produce hundreds of offspring at weekly intervals providing scientists with an ample supply of embryos? to study.
How are zebrafish used as animal models for research?
Because of its fully sequenced genome, easy genetic manipulation, high fecundity, external fertilization and rapid development, and nearly transparent embryo, zebrafish are a unique model animal for biomedical research, including studies of biological processes and human diseases.
Where can zebrafish be kept outside of oar vivaria?
Housing of adult zebrafish (greater than 14 dpf) outside of OAR vivaria must be described and justified in the Animal Protocol and approved by the IACUC. Larvae up to 14 dpf can be kept in a laboratory space approved by the IACUC. Larvae up to 14dpf will be housed in conditioned clean water.
Are there any laws to regulate animal research?
As a consequence of these occurrences, as well as pressure from animal protection groups and the public, Congress enacted laws to regulate the care and use of laboratory animals. Currently there are several layers of oversight of animal research, which are outlined below.
What is the federal policy on laboratory animals?
THE PUBLIC HEALTH SERVICE POLICY ON HUMANE CARE AND USE OF LABORATORY ANIMALS (PHS POLICY) Another federal standard that guides the care and use of laboratory animals is the Public Health Service Policy on Humane Care and Use of Laboratory Animals (PHS Policy). PHS Policy is based on the Health Research Extension Act passed by Congress in 1985.
Why was animal research not included in the AWA?
In passing the AWA, Congress left the definition of “animal” (that is, which species would be protected by the AWA) to the discretion of the Secretary of Agriculture, who opted not to include these species, primarily because the USDA has not had the resources to inspect all of these facilities.