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What disease is treated with phenylpropanolamine?

What disease is treated with phenylpropanolamine?

Phenylpropanolamine is used to treat the congestion associated with allergies, hay fever, sinus irritation, and the common cold.

Why was phenylpropanolamine taken off the market?

Phenylpropanolamine has been voluntarily removed from the market in the United States by its manufactures because of concerns raised about its ability to precipitate a stroke when used, or perhaps abused, as an appetite suppressant Kernan et al (2000).

What is the uses of phenylpropanolamine?

This combination medication is used to temporarily treat cough, chest congestion, and stuffy nose symptoms caused by the common cold, flu, allergies, hay fever, or other breathing illnesses (e.g., sinusitis, bronchitis).

What is phenylpropanolamine found in?

Phenylpropanolamine (PPA) is a drug structurally related to amphetamine, though less potent. Its use is not under the Food and Drug Administration restrictions that apply to amphetamine, and it is found in over-the-counter medications, including nasal decongestants, cough and cold remedies, and appetite suppressants.

What is paracetamol phenylpropanolamine?

Paracetamol is an analgesic (pain reliever) and antipyretic (fever reducer). It blocks the release of certain chemical messengers in the brain that cause pain and fever. Phenylpropanolamine is a decongestant which narrows the small blood vessels providing relief from congestion or stuffiness in the nose.

Is phenylpropanolamine safe for high blood pressure?

Phenylpropanolamine increased SBP 5.5 mmHg (95% CI: 3.1-8.0) and DBP 4.1 mmHg (95% CI: 2.2-6.0) with no effect on pulse. Patients with controlled hypertension were not at greater risk of blood pressure elevation. Immediate release preparations had greater effects on blood pressure than sustained release ones.

Can you still buy phenylpropanolamine?

In the United States, PPA is no longer sold due to an increased risk of haemorrhagic stroke. In a few countries in Europe, however, it is still available either by prescription or sometimes over-the-counter.

Is phenylpropanolamine safe?

In 1976, one expert panel recommended that phenylpropanolamine be generally recognized as safe and effective as a nasal decongestant, and in 1982 another expert panel recommended that phenylpropanolamine be generally recognized as safe and effective for weight control.

What schedule drug is phenylpropanolamine?

Phenylpropanolamine (PPA) is a sympathomimetic agent which is used as a decongestant and appetite suppressant….Phenylpropanolamine.

Clinical data
ATC code R01BA01 (WHO) QG04BX91 (WHO)
Legal status
Legal status AU : S4 (Prescription only) CA : Schedule VI US : Prohibited
Pharmacokinetic data

What is the meaning of phenylpropanolamine?

Phenylpropanolamine (PPA) is a sympathomimetic agent which is used as a decongestant and appetite suppressant. It was commonly used in prescription and over-the-counter cough and cold preparations. In veterinary medicine, it is used to control urinary incontinence in dogs.

Is phenylpropanolamine safe for hypertension?

Phenylpropanolamine increased SBP 5.5 mmHg (95% CI: 3.1–8.0) and DBP 4.1 mmHg (95% CI: 2.2–6.0) with no effect on pulse. Patients with controlled hypertension were not at greater risk of blood pressure elevation. Immediate release preparations had greater effects on blood pressure than sustained release ones.

Can you take paracetamol and phenylpropanolamine together?

Interactions between your drugs No interactions were found between Paracetamol and phenylpropanolamine. This does not necessarily mean no interactions exist.