What does a granulocytopenia mean?

What does a granulocytopenia mean?

Granulocytopenia is defined as a decrease of peripheral blood granulocytes below lower limit of normal range. Patients with severe granulocytopenia – agranulocytosis exhibit < 0.5 × 109/l granulocytes in peipheral blood.

Is leukopenia a form of cancer?

Different types of cancer, including leukemia, can lead to leukopenia. Cancer treatments can also cause leukopenia, including: chemotherapy. radiation therapy (especially when used on large bones, such as those in your legs and pelvis)

What does it mean when you have leukopenia?

A low white blood cell count (leukopenia) is a decrease in disease-fighting cells (leukocytes) in your blood. Leukopenia is almost always related to a decrease in a certain type of white blood cell (neutrophil). The definition of low white blood cell count varies from one medical practice to another.

What is the most common cause of leukopenia?

Blood cell and bone marrow conditions: These can lead to leukopenia. Examples include aplastic anemia, overactive spleen, and myelodysplastic syndromes. Cancer: Leukemia and other cancers may damage the bone marrow and lead to leukopenia. Infectious diseases: Examples include HIV, AIDS, and tuberculosis.

Can leukopenia be normal?

A complete lack of one of the other granulocytic series is also abnormal and may have an impact on innate immunity, but is rarely a cause of a depressed total white blood cell count. The definition of “leukopenia” varies, but in most laboratories the lower limit of a normal total white cell count is 3000/μl to 4000/μl.

What happens when your body can’t produce white blood cells?

Aplastic anemia occurs when your bone marrow doesn’t make enough red and white blood cells, and platelets. This condition can make you feel tired, raise your risk of infections, and make you bruise or bleed more easily.

Can leukopenia turn into leukemia?

Neutropenia that has been present since childhood may indicate the presence of a congenital syndrome. Leukopenia that develops acutely should prompt an evaluation for drug-induced agranulocytosis, acute infections, or acute leukemia.

What does it mean to have granulocytopenia in blood?

Granulocytopenia is defined as a decrease of peripheral blood granulocytes below lower limit of normal range. Patients with severe granulocytopenia – agranulocytosis exhibit < 0.5 × 109/l granulocytes in peipheral blood.

What is the difference between neutropenia and leukopenia?

Neutrophils are the white blood cells that protect you from fungal and bacterial infections. Leukopenia is so often caused from a decrease in neutrophils that some people use the terms “leukopenia” and “neutropenia” interchangeably.

What are the causes of leukopenia in the blood?

Many diseases and conditions can cause leukopenia, such as: Blood cell or bone marrow conditions. These include: aplastic anemia; hypersplenism, or overactive spleen

What causes granulomas in the bone marrow and leukopenia?

Sarcoidosis is a systemic illness caused by an exaggerated immune response and characterized by formation of granulomas, or small areas of inflammation, in multiple systems in your body. When these granulomas form in your bone marrow, leukopenia can result.