What is the half life of pantoprazole?

What is the half life of pantoprazole?

Pantoprazole is extensively metabolized in the liver, has a total serum clearance of 0.1 l/h/kg, a serum elimination halflife of about 1.1 h, and an apparent volume of distribution of 0.15 l/kg.

Is pantoprazole discontinued?

Actavis discontinued pantoprazole 20 mg tablets in October 2014.

Is pantoprazole hard on your liver?

Pantoprazole therapy is associated with a low rate of transient and asymptomatic serum aminotransferase elevations and is a rare cause of clinically apparent liver injury.

Does Pantoprazole heal the esophagus?

Pantoprazole is used to allow the esophagus to heal and prevent further damage to the esophagus in adults with GERD. It is also used to treat conditions where the stomach produces too much acid, such as Zollinger-Ellison syndrome in adults.

Can I take pantoprazole at night?

Available in capsule and powder form, the 40-mg dose given at bedtime has been shown to be superior to pantoprazole 40 mg given at dinner in control of overnight pH.

Is pantoprazole bad for your kidneys?

The use of proton pump inhibitors – including Prevacid (lansoprazole), Prilosec (omeprazole), Protonix (pantoprazole), and Nexium (esomeprazole) – has been linked to an increased risk of kidney damage, kidney failure, and other serious side effects.

Can I take pantoprazole only when needed?

If you take it on prescription, you may only need to take it for a few weeks or months, depending on your illness. Sometimes your doctor may advise you to take it for longer, even for many years. Your doctor may suggest taking pantoprazole only when you have symptoms. This means you won’t have to take it every day.

How safe is pantoprazole?

PPI have minimal side effects and few slight drug interactions and are considered safe for long term treatment. Pantoprazole is significantly effective both for acute and long-term treatment with excellent control of relapse and symptoms. It is well tolerated even for long-term therapy and its tolerability is optimal.

Can a 40 mg pantoprazole be taken without food?

Pantoprazole sodium delayed-release tablets should be swallowed whole, with or without food in the stomach. If patients are unable to swallow a 40 mg tablet, two 20 mg tablets may be taken. Concomitant administration of antacids does not affect the absorption of pantoprazole sodium delayed-release tablets. Contraindications

Can You take Two doses of pantoprazole at the same time?

Do not take 2 doses at the same time. Swallow Pantoprazole Sodium Delayed-Release Tablets whole, with or without food in the stomach. For patients unable to swallow a 40 mg tablet, two 20 mg tablets may be taken. Concomitant administration of antacids does not affect the absorption of Pantoprazole Sodium Delayed-Release Tablets.

Can you take pantoprazole sodium delayed release tablets whole?

Swallow Pantoprazole sodium delayed-release tablets whole, with or without food in the stomach. Concomitant administration of antacids does not affect the absorption of Pantoprazole sodium delayed-release tablets.

How often should you take pantoprazole for stomach acid?

For chronic conditions that cause the body to overproduce stomach acid, most notably Zollinger-Ellison syndrome, pantoprazole is usually taken twice per day for life. Treatment will usually start at 40 mg or 80 mg per day. It may be increased up to 240 mg per day.