Table of Contents
What is the main cause of dyslipidemia?
Dyslipidemia is classified into primary and secondary dyslipidemia. Primary causes are single or multiple gene mutations that result in either overproduction or defective clearance of triglycerides (TG) and low-density lipoprotein (LDL), or in underproduction or excessive clearance of high-density lipoprotein (HDL).
Which conditions are associated with dyslipidemia?
Dyslipidemia is defined as having blood lipid levels that are too high or low….These risk factors include:
- obesity.
- a sedentary lifestyle.
- a lack of regular physical exercise.
- alcohol use.
- tobacco use.
- use of illegal or illicit drugs.
- sexually transmitted infections.
- type 2 diabetes.
What is the link between dyslipidemia and CAD?
Dyslipidemia is a primary, widely established as an independent major risk factor for coronary artery disease (CAD) and may even be a prerequisite for CAD, occurring before other major risk factors come into play. [9] Studies have reported higher prevalence of lipid abnormalities among Asians compared with non-Asians.
What is the effect of dyslipidemia?
However, dyslipidemia can lead to cardiovascular disease, which can be symptomatic. High LDL cholesterol levels are associated with coronary artery disease (CAD), which is blockage in the arteries of your heart, and peripheral artery disease (PAD), which is blockage in the arteries of your legs.
What is the pathophysiology of dyslipidemia?
The key components viz., central obesity and insulin resistance form the basis of pathophysiology of dyslipidemia, lack of glucose tolerance, existence of chronic subclinical inflammation and hypertension in metabolic syndrome. The most accepted hypothesis describing metabolic syndrome is insulin resistance.
Is dyslipidemia the same as high cholesterol?
Have you ever been told that you have bad or unhealthy cholesterol levels? If so, your doctor might have used the term “dyslipidemia” to describe your condition. Dyslipidemia covers more than just bad cholesterol, however. It also describes an excess of triglycerides— components of fats and oils—in your blood.
What is the focus of drug treatment for dyslipidemia?
The focus of lipid-lowering therapy with drugs is prevention of complications of atherosclerosis.
What is the difference between dyslipidemia and hypertriglyceridemia?
When triglycerides are only affected, this may be referred to as hypertriglyceridemia (high triglyceride levels) or hypotriglyceridemia (low triglyceride levels). Conversely, if an individual has both triglyceride and cholesterol levels affected, this is referred to as a “combined” or “mixed” dyslipidemia.
What is dyslipidemia and how does it lead to atherosclerosis?
Dyslipidemia (Dys), the commonest cause of cardiovascular diseases, leads to lipid deposits on the arterial wall, thereby aggravating the process of atherosclerosis.
Is dyslipidemia a risk factor for heart disease?
Introduction: Dyslipidemia may be defined as increased levels of serum total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), triglycerides (TG), or a decreased serum high-density lipoprotein cholesterol (HDL-C) concentration. Dyslipidemia is an established risk factor for cardiovascular disease (CVD).
Is dyslipidemia same as hypercholesterolemia?
Hypercholesterolemia is most commonly, but not exclusively, defined as elevated levels of low-density lipoprotein cholesterol (LDL-C) or non-high-density lipoprotein cholesterol (HDL-C); an alternative term is dyslipidemia, which encompasses elevated triglycerides, low levels of HDL-C, and qualitative lipid …
What is dyslipidemia diagnosis?
Dyslipidemia is diagnosed by measuring serum lipids. Routine measurements (lipid profile) include total cholesterol (TC), TGs, HDL cholesterol, and LDL cholesterol.
What are the causes of secondary dyslipidemia?
Secondary dyslipidemia, on the other hand, is more common and occurs due to a variety of factors involving certain aspects of your lifestyle or certain medical conditions you may have. Secondary hyperlipidemias may be caused by: Poor or high fat, high sugar diet. Lack of exercise.
What does dyslipidemia stand for in medical terms?
Hyperlipidemia refers to high levels of LDL or triglycerides. Dyslipidemia can refer to levels that are either higher or lower than the normal range for those blood fats. Among the specific types…
What kind of treatment do you get for dyslipidemia?
Treatment for dyslipidemia will usually involve taking medication. A doctor will usually focus on lowering a person’s levels of triglycerides and LDL. However, treatment can vary, depending on the underlying cause of dyslipidemia and how severe it is.
Diet and Weight Management Lifestyle modifications are the first-line intervention in the management of diabetes dyslipidemia, and include weight loss, dietary modification, and aerobic exercise. Obesity increases insulin resistance and is associated with increased triglycerides and LDL cholesterol and decreased HDL cholesterol.
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