Table of Contents
What level of CA125 indicates cancer?
While a CA 125 level over 35 may indicate cancer, it does not always mean the person has cancer….CA 125 Levels Chart.
| CA 125 Levels (units/mL) | Potential Cancer |
|---|---|
| 0 – 35 (normal) | Unlikely to have cancer. 99% of the time, it means no cancer. |
| >35 (high) | Possible cancer. More tests will be needed for a diagnosis. |
Does CA125 detect all cancers?
An increased CA125 value can occur in both cancers and non-cancerous conditions.
Why did my doctor order a CA 125 blood test?
A CA-125 blood test is often ordered to monitor the progression of ovarian cancer. Baseline CA-125 levels are measured before someone undergoes treatment for ovarian cancer. A drop in CA-125 levels during and after treatment usually indicates that treatment has been successful.
What is the symptoms of CA125?
When should I request a CA125 blood test? Symptoms including persistent bloating, feeling full quickly and/or loss of appetite, pelvic or abdominal pain and needing to wee more often or urgently than usual are sometimes caused by ovarian cancer.
Can stress cause CA-125 to rise?
The most popular current theories suggest that CA 125 is synthesized by mesothelial cells in response to stress, which can be either mechanical stress caused by fluid overload, or inflammatory stress instigated by the release of mediators such as TNFα and interleukins [5,6].
What happens if CA-125 is high?
If your CA 125 level is higher than normal, you may have a benign condition, or the test result could mean that you have ovarian, endometrial, peritoneal or fallopian tube cancer. Your doctor may recommend other tests and procedures to determine your diagnosis.
Does CA 125 blood test detect all cancers?
A CA 125 test measures the amount of the protein CA 125 (cancer antigen 125) in your blood. A CA 125 test may be used to monitor certain cancers during and after treatment. In some cases, a CA 125 test may be used to look for early signs of ovarian cancer in people with a very high risk of the disease.
What does a CA125 test Tell an oncologist?
The CA-125 test is a measure of inflammation. Although a high number can mean ovarian cancer, there are many other things that can elevated it. Any inflammation in the pelvis or abodomen has the potential to raise it.
Does an elevated CA-125 test indicate cancer?
The most common use of the test is the monitoring of people with a known cancer that elevates CA 125 level, such as ovarian cancer. Around 75% to 85% of women with epithelial ovarian cancer will have an elevated CA 125 level. In the patient who is known to have a malignancy, such as ovarian cancer, the CA 125 level can be monitored periodically.
Is CA125 a reliable indicator?
Serial changes in CA125 can be used as a reliable indicator of disease response or progression so that patients can be classified as responding or progressing according to either standard or CA125 criteria.
What causes a high CA125 result?
Further, a number of benign conditions can cause elevations of the CA 125 level, including pregnancy, endometriosis, uterine fibroids (benign tumors), pancreatitis, normal menstruation, pelvic inflammatory disease, and cirrhosis of the liver. Benign tumors or cysts of the ovaries can also cause an abnormal test result.