Why is there a large number of mitochondria in the loop of Henle?

Why is there a large number of mitochondria in the loop of Henle?

In the kidney, the proximal tubule, the loop of Henle, the distal tubule and the collecting duct all require active transport to reabsorb ions4. As such, they contain more mitochondria than any other structure in the kidney.

What does the mitochondria do in the kidney?

The resting metabolic rate for the kidney is high because the kidney requires an abundance of mitochondria to provide sufficient energy to enable it to remove waste from the blood, reabsorb nutrients, regulate the balance of electrolytes and fluid, maintain acid–base homeostasis, and regulate blood pressure.

Do kidney cells have mitochondria?

Mitochondria are complex cellular organ- elles widely studied in ageing and in the function of metabolically active organs, which include the kidneys. As our cellular power plants, the mitochondria have the unenviable task of generating the majority of ATP required for cellular function.

What would happen if the mitochondria in the kidney cells were to decrease in function?

Which scenario is most likely to occur if the mitochondria in the kidney cells were to decrease in function? The amount of active transport in the kidneys would significantly decrease. The contents drawn into the cell are isolated from the cytoplasm preventing them from altering cellular function.

What is the importance of having a long loop of Henle and short loop of Henle in a nephron?

Loop of Henle, long, U-shaped portion of the tubule that conducts urine within each nephron of the kidney of reptiles, birds, and mammals. The principal function of the loop of Henle appears to be the recovery of water and sodium chloride from the urine…..

Where is mitochondria found in the nephron?

The density of mitochondria varies along the nephron, and while it is high in the proximal tubule (Fig. 2), it is actually higher in more distal parts such as the thick ascending limb of the loop of Henle.

Why is mitochondrial function important?

They help turn the energy we take from food into energy that the cell can use. But, there is more to mitochondria than energy production. Present in nearly all types of human cell, mitochondria are vital to our survival. They generate the majority of our adenosine triphosphate (ATP), the energy currency of the cell.

Which scenario would likely occur if mitochondria in the kidney cells were to decline in function?

Which scenario is most likely to occur if the mitochondria in the kidney cells were to decrease in function? The amount of active transport in the kidneys would significantly decrease.

What is the function of the loop of the Henle?

Loop of Henle, long, U-shaped portion of the tubule that conducts urine within each nephron (q.v.) of the kidney of reptiles, birds, and mammals.

Which is part of the loop of Henle contains potassium?

The loop of Henle is a heterogenous segment, comprising the pars recta of the proximal tubule, the thin descending and ascending limbs, and the medullary and cortical thick ascending limbs of the loop of Henle. There is net potassium reabsorption in the loop of Henle and <10% of the filtered load reaches the early distal tubule (see Figure 2 ).

What happens to sodium chloride in the loop of Henle?

As the liquid returns through the ascending limb, sodium chloride diffuses out of the tubule into the surrounding tissue, where its concentration is lower. In the third segment of the loop, the tubule wall can, if necessary, effect further removal of salt, even against the concentration gradient, in an active-transport process…

Is the loop of Henle lined with squamous epithelium?

The thin part of the loop of Henle is lined by simple squamous epithelium. The thin limb is divided into two parts: the ascending and descending limbs. The descending limb is highly permeable to water, but not to salt. Permeability is largely dependent on the concentration of Aquaporin 1 in the epithelium.