Table of Contents
What is the phenotype of hemophilia?
The clinical phenotype of severe hemophilia consists of spontaneous joint and muscle bleeds [1]. Typically, the onset of bleeding is early, coinciding with increasing physical activity. However, even in patients with severe hemophilia the age of first joint bleed shows a wide range.
What is the phenotype of an individual XHY normal male carrier male hemophiliac male?
Expression and Transmission
| Phenotype | Genotype |
|---|---|
| Normal male | XHY |
| Normal female | XHXH |
| Affected male | XhY |
| Carrier female | XhXH |
What is the genotype of hemophiliac female?
Inheritance of Sex-Linked Traits The female had the genotype XHXh, and produced the two gametes seen at the left side of the diagram. The male had the genotype XHY0, and produced the two gametes seen at the right side of the diagram.
Which is true of a woman with the genotype XHXh?
The Xh gene is recessive. That means in a pair of XHXh, the XH will dominate over Xh and the woman will not be haemophilic. However, she will be a carrier for future generations and can cause haemopholia in her children.
Is Hemophilia A genotype or phenotype?
Haemophilia was previously regarded as a classical example of Mendelian inheritance, with mutation in only a single gene (F8 or F9) causing the disease phenotype. The disease manifests complete penetrance. Studies, however, revealed the striking genetic and phenotypic heterogeneities of the disease.
Is PP genotype or phenotype?
Predicting Offspring Phenotypes P is dominant to p, so offspring with either the PP or Pp genotype will have the purple-flower phenotype.
What is the phenotype of an individual?
A phenotype is an individual’s observable traits, such as height, eye color, and blood type. The genetic contribution to the phenotype is called the genotype. Some traits are largely determined by the genotype, while other traits are largely determined by environmental factors.
What are the genotypes of all the individuals with hemophilia?
The genotypes of the males in a pedigree for sex-linked inheritance are easy to determine since normal blood clotting (N) is dominant and hemophilia is recessive (n). Since these alleles are on the X chromosome only, a male represented by a clear square will have the genotype XNY. A darkened square will be X”Y.
What does the genotype XHXh represent?
What does the genotype XHXh indicate? Hemophilia is sex-linked and caused by a recessive allele. A woman’s father has hemophilia, but her husband does not.
What does the genotype XHXh indicate?
The genotype for a woman with hemophilia will be: XhXh. Where ‘Xh’ means gene carrying the mutation for hemophilia present in the X chromosome.
What is the phenotype of an individual with the genotype PP?
P is dominant to p, so offspring with either the PP or Pp genotype will have the purple-flower phenotype. Only offspring with the pp genotype will have the white-flower phenotype.