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Does Depakote ER make you sleepy?
A: Common side effects experienced with Depakote include drowsiness, nausea, abdominal pain, diarrhea, vomiting, low platelet count, tremors, tiredness, and hair loss. The side effects may be mild to moderate, but they may also be signs of a more serious condition.
What drugs should not be taken with Benadryl?
Examples of medications that may interact with Benadryl include:
- antidepressants.
- stomach ulcer medicine.
- cough and cold medicine.
- other antihistamines.
- diazepam (Valium)
- sedatives.
What is contraindicated with Depakote?
Depakote is contraindicated in patients with known hypersensitivity to the drug [see Warnings and Precautions (5.11)]. Depakote is contraindicated in patients with known urea cycle disorders [see Warnings and Precautions (5.5)]. Hepatic failure resulting in fatalities has occurred in patients receiving valproate.
How long does it take for Depakote ER to kick in?
Tablets take 4 hours to reach a peak, Depakote sprinkles take just over three. Food can delay the absorption of Depakote (food has a more significant effect on the tablets compared with the sprinkles). It may take several weeks of regular dosing before an effect on mood or seizure frequency is reported.
What is the difference between Depakote and Depakote ER?
The “ER” in Depakote ER stands for Extended Release. Available in two strengths, Depakote ER contains the same active ingredient as Depakote Delayed-Release Tablets but it is designed to slowly deliver the medication over a 24-hour period. This means that Depakote ER only has to be taken once a day.
How long does Depakote ER stay in your system?
When taken by itself, the half-life of Depakote is roughly 14 hours, and it takes five half-lives to eliminate most drugs. So, while the levels of Depakote may not be high enough to have clinical effects, Depakote can remain in your system for about three days following a single dose.
How many drug interactions are there with Depakote?
Depakote (divalproex sodium) Drug Interactions. A total of 758 drugs (5396 brand and generic names) are known to interact with Depakote (divalproex sodium). 22 major drug interactions (68 brand and generic names) 685 moderate drug interactions (4974 brand and generic names) 51 minor drug interactions (354 brand and generic names)
What’s the difference between Depakote ER and ER?
Depakote ER has been confused with Depakote (no “ER” at the end of the name). This is a different form of the same medicine, but it needs to be taken more frequently than once a day. Depakote is considered a “delayed-release” medicine.
How many mg of Depakote ER should I take?
Depakote ER should be swallowed whole and should not be crushed or chewed (2.1, 2.2). • Mania: Initial dose is 25 mg/kg/day, increasing as rapidly as possible to achieve therapeutic response or desired plasma level (2.1). The maximum recommended dosage is 60 mg/kg/day (2.1, 2.2).
What’s the difference between Depakote EC and Dr?
Sometimes doctors refer to the delayed-release Depakote as Depakote “EC”-for enteric coating–or Depakote “DR” -for delayed release. When doctors use these unnecessary abbreviations (EC and DR) on prescriptions, pharmacists may think the doctor intended to write “ER.”