What is sodium Aurothiomalate used for?

What is sodium Aurothiomalate used for?

Sodium aurothiomalate is indicated for the treatment of adult and juvenile rheumatoid arthritis American Medical Association (1980) that is unresponsive to conventional chemotherapy. Gold sodium thiomalate is as effective as aurothioglucose in the treatment of rheumatoid arthritis Gottlieb (1977).

What does leflunomide do to your immune system?

Leflunomide decreases immune function. This may increase your risk of getting the disease the vaccine is designed to prevent.

Are gold salts poisonous?

Most toxic data are based on therapeutic toxicity. ADVERSE EFFECTS There is a high incidence of adverse reactions when gold salts are used for rheumatoid arthritis, incidence is between 5-50% (Eyring & Engleman, 1963; Davis & Hughes, 1974). The rate of serious reactions is approximately 3-5%.

What are gold salts used for?

Gold treatment includes different forms of gold salts used to treat arthritis. Gold is an effective medicine for controlling some types of arthritis and related diseases. In some people it helps relieve joint pain and stiffness reduce swelling and bone damage and reduce the chance of joint deformity and disability.

Does azathioprine cause immunosuppression?

Azathioprine inhibits purine synthesis. Purines are needed to produce DNA and RNA. By inhibiting purine synthesis, less DNA and RNA are produced for the synthesis of white blood cells, thus causing immunosuppression.

What medicines have gold in them?

Gold sodium thiomalate is a gold-containing chemical (salt) used in treating rheumatoid arthritis. Other gold salts available include injectable aurothioglucose (Solganal) and oral auranofin (Ridaura). It is not well understood exactly how gold salts work.

Which is safer methotrexate or leflunomide?

Patients who took leflunomide were more likely than those who took methotrexate to discontinue treatment but not because of adverse events. There was no significant difference between the leflunomide and methotrexate groups in the likelihood of elevated hepatic transaminase levels or weight loss.

Is chloroquine used for arthritis?

Hydroxychloroquine. Hydroxychloroquine is an antimalarial drug which is relatively safe and well-tolerated agent for the treatment of rheumatoid arthritis. Chloroquine is another antimalarial agent that is also sometimes used.

What mineral deficiency causes arthritis?

Reduced vitamin D intake has been linked to increased susceptibility to the development of rheumatoid arthritis (RA) and vitamin D deficiency has been found to be associated with disease activity in patients with RA.

Why is azathioprine bad for you?

Azathioprine may increase your risk of developing certain types of cancer, especially skin cancer and lymphoma (cancer that begins in the cells that fight infection). If you have had a kidney transplant, there may be a higher risk that you will develop cancer even if you do not take azathioprine.

What kind of Medicine is sodium aurothiomalate used for?

Sodium aurothiomalate (INN, known in the United States as gold sodium thiomalate) is a gold compound that is used for its immunosuppressive anti-rheumatic effects.

What is the dosage for aurothiomalate in adults?

What is the dosage for aurothiomalate? The usual initial adult dose is 10 mg by intramuscular injection followed by 25 mg for the second dose, then 25 to 50 mg weekly until gold toxicity or substantial clinical improvement occurs, or a cumulative dose of 1 g has been administered.

What kind of arthritis does gold sodium thiomalate treat?

Gold sodium thiomalate; aurothiomalate (Myochrysine) is a drug prescribed for the treatment of adult and juvenile rheumatoid arthritis, psoriatic arthritis, and Felty’s syndrome.