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Can phenytoin and valproic be taken together?

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Can phenytoin and valproic be taken together?

valproic acid phenytoin You may need dose adjustments or special tests in order to safely take both medications together. You should notify your doctor if you have symptoms such as drowsiness, visual problems, changes in behavior, nausea, or poor muscle coordination.

What can you not take with Depakote?

Some products that may interact with this drug include: certain antidepressants (e.g., amitriptyline, nortriptyline, phenelzine), certain antibiotics (carbapenems such as doripenem, imipenem), irinotecan, mefloquine, orlistat, other medications for seizure (e.g., ethosuximide, lamotrigine, phenytoin, rufinamide.

Is Dilantin and Depakote the same?

Are Depakote and Dilantin the Same Thing? Dilantin (phenytoin) and Depakote (divalproex sodium) are antiepileptic drugs (AEDs or anticonvulsants) used to treat epilepsy Depakote is also used to treat manic episodes associated with bipolar disorder and migraine headaches.

What can Dilantin be mixed with?

Dilantin can be given diluted with normal saline. The addition of parenteral Dilantin to dextrose and dextrose-containing solutions should be avoided due to lack of solubility and resultant precipitation.

What is the result of the use of phenytoin and valproic acid in combination?

This toxicity likely resulted from the drug interaction between phenytoin and valproic acid that leads to phenytoin displacement from plasmatic proteins and inhibits phenytoin metabolism, thereby increasing the concentration of free drug in the serum.

Can you take phenytoin and carbamazepine together?

carBAMazepine phenytoin This combination may alter the effects of the medication in your body. You should notify your doctor if you have loss of seizure control or symptoms such as drowsiness, visual problems, changes in behavior, nausea, or poor muscle coordination.

Will Depakote help me sleep?

Anticonvulsants vary in formulation and some have been known to improve sleep, while others may degrade sleep quality. As these medications are prescribed for many disorders, reactions to them tend to vary. Frequently used anticonvulsants include: Valproic acid (Depakote) – helps somewhat with insomnia.

Can you take phenytoin and carBAMazepine together?

What are good Depakote levels?

Ordinarily, optimal clinical response is achieved at daily doses below 60 mg/kg/day. If satisfactory clinical response has not been achieved, plasma levels should be measured to determine whether or not they are in the usually accepted therapeutic range (50 to 100 mcg/mL).

What medications should not be taken with Dilantin?

You should not use Dilantin if you also take delavirdine (Rescriptor), or if you are allergic to phenytoin, ethotoin (Peganone), fosphenytoin (Cerebyx), or mephenytoin (Mesantoin). If you are pregnant, DO NOT START TAKING this medicine unless your doctor tells you to.

What interacts with phenytoin?

Most frequently checked interactions

  • Acetylsalicylic Acid (aspirin)
  • Advair Diskus (fluticasone / salmeterol)
  • Aspirin Low Strength (aspirin)
  • Combivent (albuterol / ipratropium)
  • Coumadin (warfarin)
  • Keppra (levetiracetam)
  • Lasix (furosemide)
  • Lipitor (atorvastatin)

Are there any drug interactions with Depakote and Dilantin?

Dilantin and Depakote drug interactions – from FDA reports. Summary. Drug interactions are reported among people who take Dilantin and Depakote together. This study is created by eHealthMe based on reports of 989 people who take Dilantin and Depakote from FDA, and is updated regularly.

Are there any side effects to taking Depakote?

Common side effects of Dilantin include: rash. What Are Possible Side Effects of Depakote? Common side effects of Depakote include: hair loss. Antiepileptic drugs (AEDs), including Depakote, increase the risk of suicidal thoughts or behavior in patients taking these drugs for any indication.

What happens if you take Lamictal and Depakote together?

This combination may cause skin rash, restlessness, seizures, tremors, muscle weakness, and staggering walk. If you take both medications together, tell your doctor if you have any of these symptoms.

How much Depakote should I take for Mania?

The recommended initial dose of Depakote to treat mania is 750 mg daily in divided doses. The dose of Depakote to treat epilepsy as monotherapy should be initiated at 10 to 15 mg/kg/day. The recommended starting dose of Depakote to treat migraines is 250 mg twice daily.