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Does Soliris need to be refrigerated?
Store Soliris vials refrigerated at 2°-8° C (36°-46° F) in the original carton to protect from light until time of use. Soliris vials may be stored in the original carton at controlled room temperature (not more than 25° C/77° F) for only a single period up to 3 days.
How do you reconstitute Soliris?
Dilute Soliris to a final concentration of 5 mg/mL by adding the appropriate amount (equal volume of diluent to drug volume) of 0.9% Sodium Chloride Injection, USP; 0.45% Sodium Chloride Injection, USP; 5% Dextrose in Water Injection, USP; or Ringer’s Injection, USP to the infusion bag.
Can Soliris be infused at home?
Soliris is a treatment that is given by intravenous (IV) infusion. Some people visit an infusion center to receive Soliris while others prefer to have a visiting nurse administer their infusion at home. The location in which you receive your infusion can depend on your insurance and where you live.
Who manufactures Soliris?
BOSTON –(BUSINESS WIRE)–Jun. 27, 2019– Alexion Pharmaceuticals, Inc. (NASDAQ:ALXN) today announced that the U.S. Food and Drug Administration ( FDA ) approved SOLIRIS® (eculizumab) for the treatment of neuromyelitis optica spectrum disorder (NMOSD) in adult patients who are anti-aquaporin-4 (AQP4) antibody positive.
Is Soliris a biologic?
Soliris is classified as a monoclonal antibody. Monoclonal antibodies are a relatively new type of “targeted” cancer or biologic therapy. Antibodies are an integral part of the body’s immune system. Normally, the body creates antibodies in response to an antigen (such as a protein in a germ) that has entered the body.
How long does Soliris stay in your system?
Do not stop receiving Soliris without first talking to your doctor. Interrupting your treatment could cause sudden and serious effects on your red blood cells. Eculizumab can effect your body for up to 3 months.
What is the difference between Soliris and Ultomiris?
Although they are similar in many respects, a key difference between the two medications is that Ultomiris is not cleared from the body as quickly as Soliris, requiring less frequent infusions.
How is Ultomiris administered?
ULTOMIRIS, administered up to every 8 weeks,f gives people with PNH the possibility of more freedom and flexibility between treatments. ULTOMIRIS is given through a vein by intravenous (IV) infusion. After each infusion, you should be monitored for at least 1 hour for infusion-related reactions.
How much is SOLIRIS cost?
Priced at $678,392 per year, Soliris is used to treat paroxysmal nocturnal hemoglobinuria and atypical hemolytic uremic syndrome — blood disorders that result in the destruction of red blood cells. The dosing regimen for Soliris can differ depending on the age of the patient and the condition being treated.
How often is SOLIRIS given?
If you are an adult, you will usually receive a SOLIRIS infusion by your doctor: o weekly for five weeks, then o every 2 weeks • If you are less than 18 years of age, your doctor will decide how often you will receive SOLIRIS depending on your age and body weight • After each infusion, you should be monitored for one …
Who owns Alexion Pharmaceuticals?
AstraZeneca
Alexion Pharmaceuticals/Parent organizations
What does Alexion Pharmaceuticals make?
Alexion Pharmaceuticals, Inc. is a biopharmaceutical company, which focuses on serving patients with devastating and ultra-rare disorders through the development and commercialization of life-transforming therapeutic products. Its products include ultomiris, soliris, strensiq and kanuma.