Is caffeine citrate the same as caffeine?

Is caffeine citrate the same as caffeine?

NOTE THAT THE DOSE OF CAFFEINE BASE IS ONE-HALF THE DOSE WHEN EXPRESSED AS CAFFEINE CITRATE (e.g., 20 mg of caffeine citrate is equivalent to 10 mg of caffeine base). Serum concentrations of caffeine may need to be monitored periodically throughout treatment to avoid toxicity.

What is caffeine citrate used for?

This medication is used for the short-term treatment of a breathing problem (apnea) in premature infants. Caffeine blocks certain proteins (adenosine receptors) which lead to improved breathing in these infants.

How much caffeine in caffeine citrate?

Each mL contains 20 mg caffeine citrate (equivalent to 10 mg of caffeine base) prepared in solution by the addition of 10 mg caffeine anhydrous to 5.0 mg citric acid monohydrate, 8.3 mg sodium citrate dihydrate and Water for Injection.

What is caffeine citrate Injection?

Caffeine citrate injection or oral liquid (Cafcit) is used to treat breathing problems in premature infants. Caffeine citrate injection or oral liquid may also be used for purposes not listed in this medication guide.

What is the brand name for caffeine citrate?

BRAND NAME(S): Cafcit.

How do you administer caffeine citrate?

Intravenous injection: Using a syringe infusion pump, administer caffeine citrate dose slowly over 10 minutes into a vein or into the tubing of a freely-flowing compatible IV solution. Compatible IV solutions for Cafcit include: Dextrose 5%, Dextrose 50%, Aminosyn 8.5% solution, and Intralipid 20% emulsion.

What is brand name of caffeine?

BRAND NAME(S): Cafcit. USES: This medication is used for the short-term treatment of a breathing problem (apnea) in premature infants. Caffeine blocks certain proteins (adenosine receptors) which lead to improved breathing in these infants.

Why do they give NICU babies caffeine?

Caffeine reduces the frequency of apnea, intermittent hypoxemia, facilitates extubation from mechanical ventilation, and reduces the incidence of bronchopulmonary and patent ductus arteriosus in preterm infants.

What is the brand name of caffeine citrate?

How do you give a neonate citrate to caffeine?

The recommended loading dose of caffeine citrate is 20 mg/kg orally or intravenously followed by 5 mg/kg daily oral (or IV over 30 minutes) maintenance doses. The recommended loading dose of theophylline is 5–6 mg/kg, followed by maintenance doses of 2–6 mg/kg/day divided into two or three doses.

Can caffeine citrate injection be given orally?

(c) Caffeine Citrate 10mg/ml Solution for Injection is also effective when administered orally, and this route may be used alternatively without adjusting the dose.

Is caffeine a pharmaceutical drug?

Caffeine is a stimulant drug, which means it speeds up the messages travelling between the brain and the body. It’s found in the seeds, nuts and leaves of a number of different plants, including: Coffea Arabica (used for coffee) Thea sinensis (used for tea)

How many mg of caffeine in 20 mg of citrate?

Dose Doses expressed as caffeine citrate (NB: 20 mg caffeine citrate = 10 mg caffeine base). * Maintenance dose should commence at least 24 hours after loading dose. Reconstitution/Dilution IV ampoules = 20 mg/mL (caffeine citrate). For IV use: Can be given undiluted.

What kind of vials are used for caffeine citrate?

Caffeine Citrate injection USP is available as a clear, colorless, sterile, non-pyrogenic, preservative-free, aqueous solution in 3 mL colorless glass vials. The vials are a clear USP Type I 5 mL glass vial with grey chlorobutyl rubber stoppers with white colored, flip off aluminum seals.

Is it OK to use IV caffeine citrate?

The IV solution is usually clear and colourless – inspect for signs of discolouration, cloudiness, turbidity or particular matter prior to use. DO NOT use unless solution is clear and colourless. References: Steer PS et al. High dose caffeine citrate for extubation of preterm infants: a randomised controlled trial.

What kind of muscle relaxer is caffeine used for?

It is a bronchial smooth muscle relaxant, a CNS stimulant, a cardiac muscle stimulant, and a diuretic. Although the mechanism of action of caffeine in apnea of prematurity is not known, several mechanisms have been hypothesized.