Table of Contents
- 1 What are the side effects of ethylene glycol?
- 2 What organ does ethylene glycol effect?
- 3 What are the 3 stages to ethylene glycol poisoning?
- 4 Is ethylene glycol sweet?
- 5 How is ethylene glycol poisoning diagnosed?
- 6 How can you tell if someone has ethylene glycol poisoning?
- 7 What should I do if I swallowed ethylene glycol?
What are the side effects of ethylene glycol?
Initial adverse health effects caused by ethylene glycol intoxication include:
- central nervous system depression,
- intoxication,
- euphoria,
- stupor, and.
- respiratory depression.
- Nausea and vomiting may occur as a result of gastrointestinal irritation.
What happens if you consume ethylene glycol?
Ethylene glycol poisoning is poisoning caused by drinking ethylene glycol. Early symptoms include intoxication, vomiting and abdominal pain. Later symptoms may include a decreased level of consciousness, headache, and seizures. Long term outcomes may include kidney failure and brain damage.
What organ does ethylene glycol effect?
An overdose of ethylene glycol can damage the brain, lungs, liver, and kidneys. The poisoning causes disturbances in the body’s chemistry, including metabolic acidosis (increased acids in the bloodstream and tissues). The disturbances may be severe enough to cause profound shock, organ failure, and death.
What are the symptoms of ethylene glycol poisoning in dogs?
Signs of inappetance, lethargy, drooling, vomiting, seizures, and coma may be seen. Treatment for ethylene glycol poisoning includes the antidote fomepizole (also known as 4-MP) or ethanol. Fomepizole is expensive but life-saving when administered to dogs within the first 8-12 hours of ingestion.
What are the 3 stages to ethylene glycol poisoning?
The clinical presentation of ethylene glycol poisoning is described as three sequential phases, which are neurological, cardiopulmonary, and renal phases. Neurological symptoms, which can occur in as little as thirty minutes after ingestion, are similar to those seen in early ethanol intoxication.
Does antifreeze still taste sweet?
Most antifreeze is made from ethylene glycol. Ethylene glycol-based antifreeze tastes sweet but is highly toxic to both humans and animals. While this is a step in the right direction that will undoubtedly save lives, consumers should still be encouraged use antifreeze made from propylene glycol instead.
Is ethylene glycol sweet?
Ethylene glycol is the ingredient that makes antifreeze tasty. Though colorless and odorless, the syrupy alcohol derivative—which is excellent at lowering the freezing points of vital engine fluids—has a sweet taste that jibes well with soda, juice, and other sugary beverages.
What is propylene glycol toxicity?
Toxic effects include hyperosmolality, increased anion gap metabolic acidosis (due to lactic acidosis), acute kidney injury, and sepsis-like syndrome. Treatment of toxicity includes hemodialysis to effectively remove propylene glycol. Prevention is best achieved by limiting the dose of propylene glycol infused.
How is ethylene glycol poisoning diagnosed?
- Ethylene glycol poisoning is strongly suggested by. an elevated anion-gap metabolic acidosis, an elevated osmolal gap, and. urinary calcium oxalate or hippuric acid crystals.
- Measurement of serum ethylene glycol levels can confirm poisoning.
Can blood test detect ethylene glycol?
This test measures the level of ethylene glycol in the blood. Ethylene glycol is a type of alcohol found in automotive and household products. It does not have color or odor.
How can you tell if someone has ethylene glycol poisoning?
Following ingestion of antifreeze products containing ethylene glycol and fluorescein, a Wood’s lamp may reveal fluorescence of a person’s mouth area, clothing, vomitus, or urine which can help to diagnose poisoning.
When does Stage 3 ethylene glycol poisoning occur?
If untreated, death most commonly occurs during this period. Stage 3 (24 to 72 hours) kidney failure is the result of ethylene glycol poisoning. In cats, this stage occurs 12–24 hours after consuming antifreeze; in dogs, at 36–72 hours after consuming antifreeze.
What should I do if I swallowed ethylene glycol?
Most people with ethylene glycol poisoning need to be admitted to a hospital, often to the intensive care unit (ICU) for close monitoring. A breathing machine (respirator) may be needed. Those who recently (within 30 to 60 minutes of presentation to the emergency department) swallowed the ethylene glycol may have their stomach pumped (suctioned).
Which is the best antidote for ethylene glycol poisoning?
The preferred antidote is fomepizole with ethanol used if this is not available. Hemodialysis may also be used in those where there is organ damage or a high degree of acidosis. Other treatments may include sodium bicarbonate, thiamine, and magnesium. More than 5,000 cases of poisoning occur in the United States each year.