What does PML abbreviation mean?

What does PML abbreviation mean?

PML stands for progressive multifocal leukoencephalopathy. It’s an aggressive viral disease of the central nervous system. The virus attacks cells that make myelin. It’s a life-threatening condition. Read on to learn more about the symptoms, risk factors, and treatment for this uncommon, but serious viral disease.

What does PML stand for business?

Probable maximum loss (PML) is the maximum loss that an insurer would be expected to incur on a policy.

What is PML in healthcare?

PML: Stands for progressive multifocal leukoencephalopathy, a rapidly progressive, often fatal viral infection of the brain. Commonly abbreviated as PML. PML is believed to be due to the Jacob-Creutzfeldt (JC) papovavirus. The virus infects oligodendrocytes (support cells in the brain).

What does PML do to the brain?

Progressive multifocal leukoencephalopathy (PML) is a disease that attacks part of your brain. It happens if your body can’t fight off disease the way it should. It damages your brain’s white matter — cells that make a substance called myelin.

What is a PML study?

Probable maximum loss (PML) investigations provide an estimate of the level of earthquake losses, which could be anticipated for site buildings, given the calculated level of seismic hazard.

How do you calculate PML?

Multiply the property valuation by the highest expected loss percentage to calculate the probable maximum loss. For example, if the property valuation is $500,000 and you determine that fire risk mitigation reduces expected losses by 20 percent, probable maximum loss for a fire is $500,000 multiplied by .

Is PML an opportunistic infection?

Progressive multifocal leukoencephalopathy (PML) is an opportunistic infection of the central nervous system (CNS), caused by the polyoma virus JC virus (JCV) and characterized by focal demyelination. The virus has worldwide distribution, with a seroprevalence of 39% to 69% among adults.

What medications can cause PML?

Immunosuppressive medications that have been associated with PML include cyclophosphamide, corticosteroids, mycophenolate mofetil and monoclonal antibodies including natalizumab (Tysabri), rituximab (Mabthera) and alemtuzumab (MabCampath)8.

Is PML fatal?

Some people may experience headaches or epilepsy, although these symptoms are rare. Eventually, PML usually progresses. The condition is often fatal, but the outlook varies according to the underlying condition and response to treatment.

Has anyone ever survived PML?

A year later there was an almost complete resolution of the MRI lesions and the patient achieved a stable clinical state with persisting motor impairment and severe epilepsy. The patient is alive 38 months after diagnosis of PML, which is the longest known survival to date.

What is the difference between PML and EML?

After the term EML, the second most commonly used term is Probable Maximum Loss (PML). The PML is defined as the largest estimated loss arising from a single event which was assessed with due care, taking into account all the elements of the risk .

What is a PML report?

The Probable Maximum Loss report identifies the PML value, expressed as a percentage of the building’s replacement cost and estimates the potential damage during a 475-year earthquake – the lower the percentage, the lower the expected damage.

What does PML mean?

Definition Progressive multifocal leukoencephalopathy (PML) is a rapidly progressive neuromuscular disease caused by opportunistic infection of brain cells ( oligodendrocytes and astrocytes) by the JC virus (JCV). PML is an opportunistic infection associated with AIDS and certain cancers.

What does PML(N) stand for?

PML-N: Pakistan Muslim League (Nawaz Sharif group; Islamabad, Pakistan; political party)

What does PML mean in medical dictionary?

Progressive multifocal leukoencephalopathy (PML) is a disease that attacks part of your brain. It happens if your body can’t fight off disease the way it should.