What is the function of megakaryocyte?

What is the function of megakaryocyte?

The primary function of megakaryocytes is to synthesize and assemble platelet components and organelles. Although debated for a long time, new data seems to indicate that the lung may be a central locus of platelet production.

Is a megakaryocyte a white blood cell?

Megakaryocytes (the cells that produce platelets) and erythrocytes (red blood cells) are not formally considered to be leukocytes, but arise from the common myeloid progenitor cells that produce the other cellular components of blood.

What does the word megakaryocyte mean?

: a large cell that has a lobulated nucleus, is found especially in the bone marrow, and is the source of blood platelets.

What is a megakaryocyte quizlet?

Megakaryocyte is a bone marrow cell responsible for the production of blood platelets when its —– megakaryocytes.

Is a megakaryocyte a macrophage?

In addition to neutrophilic granulocytes and erythroblasts, megakaryocytes were present in 16 of the 73 colonies, as identified by positive reaction for acid phosphatase. Macrophages were found in 24 and eosinophils in 6 of the 73 colonies.

What does a megakaryocyte eventually become?

What does a megakaryocyte eventually become. Thrombocyte. Red bone marrow produces erythrocytes, leukocytes, and thrombocytes.

What is the purpose of a differential WBC count?

A WBC differential may be used to help diagnose the cause of a high or low white blood cell (WBC) count results seen on a CBC. It may also be used to help diagnose and/or monitor other diseases and conditions that affect one or more different types of WBCs.

Are megakaryocytes circulating?

The results confirm that circulating megakaryocytes are a normal physiologic component. During cardiopulmonary bypass, megakaryocytes with copious cytoplasm (mean diameter 42.7 microns, range 22 to 78 microns) can pass through the extracorporeal circuit.

What is megakaryocytic leukemia?

Introduction. Acute megakaryoblastic leukemia (AMKL) is a subtype of acute myeloid leukemia (AML) characterized by abnormal megakaryoblasts that express platelet-specific surface glycoprotein. Bone marrow biopsy frequently demonstrates extensive myelofibrosis, often making aspiration in these patients difficult.

What does phlebotomy mean in medical terms?

A procedure in which a needle is used to take blood from a vein, usually for laboratory testing. Phlebotomy may also be done to remove extra red blood cells from the blood, to treat certain blood disorders. Also called blood draw and venipuncture.

Where are megakaryocytes located quizlet?

Megakaryocytes are located in the red bone marrow found within spongy bone and are stimulated to release platelets into the circulation by a hormone called thrombopoietin. Thrombopoietin is primarily produced by cells in the liver, kidney, and red bone marrow.

What is the function of megakaryocytes quizlet?

What is a megakaryocyte? a large bone marrow cell with a lobulated nucleus responsible for the production of blood thrombocytes (platelets), which are necessary for normal blood clotting.

Which is the medical definition of a megakaryocyte?

Medical Definition of megakaryocyte : a large cell that has a lobulated nucleus, is found especially in the bone marrow, and is the source of blood platelets Other Words from megakaryocyte

How big is a megakaryocyte compared to a RBC?

A megakaryocyte (MK) is a large bone marrow cell about 50 to 100 micrometer (a micrometer is expressed as μm; 1 micrometer is equal to 1×10−6 of a meter), which makes it 10 to 15 times larger than a typical red blood cell (RBC). As it develops, the megakaryocyte grows in size.

Where do megakaryocytes get their platelets from?

MK Differentiation: Megakaryocytes are derived from another kind of cell in the bone marrow. Megakaryocytes (MK) are progenitor cells that produce platelets. But what produces megakaryocytes?

How are the development of megakaryocytes regulated?

Megakaryocytes development and formation are regulated by a multitude of cytokines, principally Tpo (thrombopoietin), which is produced in the liver and marrow stroma. Megakaryocytes can be classified into three stages of maturation: