Table of Contents
Which organ is responsible for malaria?
The infection develops in the liver before re-entering the bloodstream and invading the red blood cells. The parasites grow and multiply in the red blood cells. At regular intervals, the infected blood cells burst, releasing more parasites into the blood.
What caused the malaria?
Malaria is an acute febrile illness caused by Plasmodium parasites, which are spread to people through the bites of infected female Anopheles mosquitoes. There are 5 parasite species that cause malaria in humans, and 2 of these species – P. falciparum and P. vivax – pose the greatest threat.
How does malaria affect the liver?
The researchers found that the parasites kill the liver cell they occupy and make it detach from its neighbours. The infected cells then squeeze through tiny gaps in the walls of blood vessels in the liver.
How does malaria affect the kidney?
Kidney complications in malaria mainly occur due to hemodynamic dysfunction and immune response. Liver complications leading to hepatomegaly, jaundice and hepatic dysfunction can also contribute to the occurrence of acute kidney injury.
How does malaria affect the spleen?
Spleen becomes enlarged during malaria because of filtering out of excessive destroyed RBC after the hemolysis and occurs not only during malaria, during many infectious/non infecious diseases following with the RBC hemolysis.
Does malaria affect the spleen?
The spleen is a complex organ that is perfectly adapted to selectively filtering and destroying senescent red blood cells (RBCs), infectious microorganisms and Plasmodium-parasitized RBCs. Infection by malaria is the most common cause of spleen rupture and splenomegaly, albeit variably, a landmark of malaria infection.
Why does spleen enlargement occurs in malaria infection?
Where in Africa did malaria start?
The first indication that African apes harbor Plasmodium infections was the finding of three morphologically distinct forms of parasites in the blood of wild-caught chimpanzees (Pan troglodytes) and western gorillas (Gorilla gorilla) in Cameroon (Reichenow, 1920).
Who invented malaria medicine?
The discovery of a potent antimalarial treatment by Youyou Tu of China, awarded the Nobel Prize in Medicine, is “one of the greatest examples of the century” of the translation of scientific discovery, according to malaria expert Dyann Wirth of Harvard T.H. Chan School of Public Health.
Can malaria cause liver enlargement?
To conclude, it is known that long-term exposure to malaria causes chronic enlargement of the liver and the spleen and here the levels of three cytokines, IL-12p70, IL-10 and IL-13, and levels of sTNF-RII were found to be associated with both hepatosplenomegaly and exposure to malaria.