Table of Contents
- 1 Which group of people in the US is most at risk for thiamin deficiency Why?
- 2 Which patient is at the greatest risk of thiamine deficiency?
- 3 Who needs thiamine?
- 4 What causes thiamine deficiency?
- 5 What is the action of thiamine?
- 6 What causes thiamine?
- 7 What causes high thiamine levels?
- 8 What is a good source of B1?
- 9 Is there a cure or treatment for thiamine deficiency?
- 10 Why is there a thiamine shortage in the United States?
Which group of people in the US is most at risk for thiamin deficiency Why?
The risk of thiamin deficiency is increased in people who subsist on highly refined carbohydrates such as polished rice and white flour (as occurs in developing countries) or who are alcoholics.
Which patient is at the greatest risk of thiamine deficiency?
People with alcohol dependence In highly industrialized countries, chronic alcohol use disorders appear to be the most common cause of thiamin deficiency [1].
What population is especially susceptible to thiamine?
Between 25%–50% of the women and 5%–25% of the men in the United States, Germany, and the Netherlands are at risk for thiamin deficiency.
Who needs thiamine?
Most adults and children aged 12 years or older can take thiamine. Only give thiamine to a child under the age of 12 years if a specialist recommends it. Thiamine may not be suitable for some people.
What causes thiamine deficiency?
Thiamine deficiency | |
---|---|
Types | Wet, dry, gastrointestinal |
Causes | Not enough thiamine |
Risk factors | Diet of mostly white rice; alcoholism, dialysis, chronic diarrhea, diuretics |
Prevention | Food fortification |
What happens with thiamine deficiency?
An abnormally slow heart rate as result of thiamine deficiency may cause increased fatigue, dizziness and a greater risk of fainting. A thiamine deficiency may cause a decrease in heart rate, resulting in increased fatigue and dizziness.
What is the action of thiamine?
Mechanism of Action: Thiamine combines with adenosine triphosphate (ATP) in the liver, kidneys, and leukocytes to produce thiamine diphosphate. Thiamine diphosphate acts as a coenzyme in carbohydrate metabolism, in transketolation reactions, and in the utilization of hexose in the hexose-monophosphate shunt.
What causes thiamine?
Good sources of thiamin include dried yeast, whole grains, meat (especially pork and liver), enriched cereals, nuts, legumes, and potatoes. Thiamin deficiency often occurs with other B vitamin deficiencies.
Which disease is caused by a vitamin B1 deficiency?
Beriberi is a disease in which the body does not have enough thiamine (vitamin B1).
What causes high thiamine levels?
High levels of thiamine are rare but may occur if excessive amounts of the vitamin are consumed, either in supplements or from foods.
What is a good source of B1?
Food Sources
- Fortified breakfast cereals.
- Pork.
- Fish.
- Beans, lentils.
- Green peas.
- Enriched cereals, breads, noodles, rice.
- Sunflower seeds.
- Yogurt.
What are the risk factors for thiamine deficiency?
Risk factors for thiamine deficiency include: Thiamine deficiency is rare in the developed world because many foods have supplemental thiamine added. Though the disease is uncommon, you can reduce your risk of thiamine deficiency by eating a healthy and varied diet.
Is there a cure or treatment for thiamine deficiency?
Because it is rare, most people with risk factors will not get thiamine deficiency. However, those who are experiencing the following may be more at risk: The only treatment for thiamine deficiency is thiamine supplementation and changes to any underlying dietary habits that may have caused the deficiency.
Why is there a thiamine shortage in the United States?
The very general reason for beriberi in the U.S.A is the action of alcohol on the human system. Too much use of alcohol may reduce the body’s capacity to take up thiamine, leading to a shortage. Sometimes, it may be hereditary. It may also attack babies whose mother’s eating habits are insufficient in thiamine ( 01).
What are the rare genetic diseases of thiamine transport?
Genetic diseases of thiamine transport are rare but serious. Thiamine responsive megaloblastic anemia syndrome (TRMA) with diabetes mellitus and sensorineural deafness is an autosomal recessive disorder caused by mutations in the gene SLC19A2, a high affinity thiamine transporter.